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1

Evaluation of Pancreatic VMAT2 Binding with Active and Inactive Enantiomers of [18F]FP-DTBZ in Healthy Subjects and Patients with Type 1 Diabetes

Naganawa, Mika, Lim, Keunpoong, Nabulsi, Nabeel B., Lin, Shu-fei, Labaree, David, Ropchan, Jim, Herold, Kevan C., Huang, Yiyun, Harris, Paul, Ichise, Masanori, Cline, Gary W., Carson, Richard E.

Journal:

Molecular Imaging and Biology

Year:

2018

Language:

english

File:

PDF, 2.40 MB

english, 2018

2

Strength in Numbers: Opportunities for Enhancing the Development of Effective Treatments for Type 1 Diabetes—The TrialNet Experience

Greenbaum, Carla J., Speake, Cate, Krischer, Jeffrey, Buckner, Jane, Gottlieb, Peter A., Schatz, Desmond A., Herold, Kevan C., Atkinson, Mark A.

Journal:

Year:

2018

Language:

english

File:

PDF, 1.02 MB

english, 2018

3

Autoimmune Endocrinopathies: An Emerging Complication of Immune Checkpoint Inhibitors

Quandt, Zoe, Young, Arabella, Perdigoto, Ana Luisa, Herold, Kevan C., Anderson, Mark S.

Journal:

Annual Review of Medicine

Year:

2021

File:

PDF, 2.17 MB

2021

4

Standardizing T-Cell Biomarkers in Type 1 Diabetes: Challenges and Recent Advances

Ahmed, Simi, Cerosaletti, Karen, James, Eddie, Long, S. Alice, Mannering, Stuart, Speake, Cate, Nakayama, Maki, Tree, Timothy, Roep, Bart O., Herold, Kevan C., Brusko, Todd M.

Journal:

Year:

2019

Language:

english

File:

PDF, 1.87 MB

english, 2019

5

Genetics, pathogenesis and clinical interventions in type 1 diabetes

Bluestone, Jeffrey A., Herold, Kevan, Eisenbarth, George

Journal:

Year:

2010

Language:

english

File:

PDF, 7.38 MB

english, 2010

6

Corrigendum: A carbon nanotube–polymer composite for T-cell therapy

Fadel, Tarek R., Sharp, Fiona A., Vudattu, Nalini, Ragheb, Ragy, Garyu, Justin, Kim, Dongin, Hong, Enping, Li, Nan, Haller, Gary L., Pfefferle, Lisa D., Justesen, Sune, Herold, Kevan C., Fahmy, Tarek

Journal:

Nature Nanotechnology

Year:

2014

File:

PDF, 522 KB

2014

7

Continuous glucose monitoring: long live the revolution!

Waldron-Lynch, Frank, Herold, Kevan C

Journal:

Nature Clinical Practice Endocrinology and Metabolism

Year:

2009

Language:

english

File:

PDF, 149 KB

english, 2009

8

Benefits and Risks of Exercise

Herold, Kevan C.

Journal:

JAMA The Journal of the American Medical Association

Year:

1983

Language:

english

File:

PDF, 169 KB

english, 1983

9

The role of AIRE in human autoimmune disease

Akirav, Eitan M., Ruddle, Nancy H., Herold, Kevan C.

Journal:

Nature Reviews Endocrinology (formerly Nature Clinical Practice Endocrinology & Metabolism)

Year:

2011

Language:

english

File:

PDF, 315 KB

english, 2011

10

Immunotherapy of Type 1 Diabetes: Where Are We and Where Should We Be Going?

Xunrong Luo, Kevan C. Herold, Stephen D. Miller

Journal:

Year:

2010

Language:

english

File:

PDF, 282 KB

english, 2010

11

Characterization of residual β cell function in long-standing type 1 diabetes

Sherr, Jennifer L., Ghazi, Tara, Wurtz, Anna, Rink, Linda, Herold, Kevan C.

Journal:

Year:

2014

Language:

english

File:

PDF, 366 KB

english, 2014

12

Evaluation of PET Brain Radioligands for Imaging Pancreatic β-Cell Mass: Potential Utility of 11 C-PHNO

Bini, Jason, Naganawa, Mika, Nabulsi, Nabeel B, Huang, Yiyun Henry, Ropchan, Jim, Lim, Keunpoong, Najafzadeh, Soheila, Herold, Kevan C, Cline, Gary W, Carson, Richard E

Journal:

Journal of Nuclear Medicine

Year:

2018

Language:

english

File:

PDF, 1.11 MB

english, 2018

13

TREATMENT OF SEVERELY PAINFUL DIABETIC NEUROPATHY WITH AN ALDOSE REDUCTASE INHIBITOR: RELIEF OF PAIN AND IMPROVED SOMATIC AND AUTONOMIC NERVE FUNCTION

Jaspan, Jonathan, Herold, Kevan, Maselli, Ricardo, Bartkus, Cynthia

Journal:

Year:

1983

Language:

english

File:

PDF, 735 KB

english, 1983

14

Methylation of insulin DNA in response to proinflammatory cytokines during the progression of autoimmune diabetes in NOD mice

Rui, Jinxiu, Deng, Songyan, Lebastchi, Jasmin, Clark, Pamela L., Usmani-Brown, Sahar, Herold, Kevan C.

Journal:

Year:

2016

Language:

english

File:

PDF, 911 KB

english, 2016

15

Progress and challenges for treating Type 1 diabetes

Garyu, Justin W., Meffre, Eric, Cotsapas, Chris, Herold, Kevan C.

Journal:

Journal of Autoimmunity

Year:

2016

Language:

english

File:

PDF, 813 KB

english, 2016

16

Oxidative Modifications in Tissue Pathology and Autoimmune Disease

Yang, Mei-ling, Doyle, Hester, Clarke, Steven G, Herold, Kevan, Mamula, Mark

Journal:

Antioxidants & Redox Signaling

Year:

2017

Language:

english

File:

PDF, 1.60 MB

english, 2017

17

Anti-CD3 mAbs for treatment of type 1 diabetes

Adam Kaufman, Kevan C. Herold

Journal:

Diabetes/Metabolism Research and Reviews

Year:

2009

Language:

english

File:

PDF, 86 KB

english, 2009

18

Antigen-based therapy with glutamic acid decarboxylase (GAD) vaccine in patients with recent-onset type 1 diabetes: a randomised double-blind trial

Diane K Wherrett, Brian Bundy, Dorothy J Becker, Linda A DiMeglio, Stephen E Gitelman, Robin Goland, Peter A Gottlieb, Carla J Greenbaum, Kevan C Herold, Jennifer B Marks, Roshanak Monzavi, Antoinette

Journal:

Year:

2011

Language:

english

File:

PDF, 405 KB

english, 2011

19

Receptor for Advanced Glycation End Products and the Cardiovascular Complications of Diabetes and Beyond: Lessons from AGEing

Yan, Shi Fang, Yan, Shi Du, Herold, Kevan, Ramsamy, Ravichandran, Schmidt, Ann Marie

Journal:

Endocrinology and Metabolism Clinics of North America

Year:

2006

Language:

english

File:

PDF, 153 KB

english, 2006

20

Biomarkers in type 1 diabetes

Tooley, James E., Herold, Kevan C.

Journal:

Current Opinion in Endocrinology Diabetes and Obesity

Year:

2014

Language:

english

File:

PDF, 221 KB

english, 2014

21

INHIBITION OF GLUCOSE-STIMULATED INSULIN RELEASE FROM βTC3 CELLS AND RODENT ISLETS BY AN ANALOG OF FK506

HEROLD, KEVAN C., NAGAMATSU, SHINYA, BUSE, JOHN B., KULSAKDINUN, PAMORN, STEINER, DONALD F.

Journal:

Transplantation Journal

Year:

1993

File:

PDF, 769 KB

1993

22

Identification and Analysis of Islet Antigen–Specific CD8 + T Cells with T Cell Libraries

Ogura, Hideki, Preston-Hurlburt, Paula, Perdigoto, Ana Luisa, Amodio, Matthew, Krishnaswamy, Smita, Clark, Pamela, Yu, Hua, Egli, Dieter, Fouts, Alexandra, Steck, Andrea K., Herold, Kevan C.

Journal:

The Journal of Immunology

Year:

2018

Language:

english

File:

PDF, 2.07 MB

english, 2018

23

An Anti-CD3 Antibody, Teplizumab, in Relatives at Risk for Type 1 Diabetes

Herold, Kevan C., Bundy, Brian N., Long, S. Alice, Bluestone, Jeffrey A., DiMeglio, Linda A., Dufort, Matthew J., Gitelman, Stephen E., Gottlieb, Peter A., Krischer, Jeffrey P., Linsley, Peter S., Mar

Journal:

New England Journal of Medicine

Year:

2019

File:

PDF, 367 KB

2019

24

Type 1 diabetes: translating mechanistic observations into effective clinical outcomes

Herold, Kevan C., Vignali, Dario A. A., Cooke, Anne, Bluestone, Jeffrey A.

Journal:

Nature Reviews Immunology

Year:

2013

Language:

english

File:

PDF, 697 KB

english, 2013

25

The Development and Utility of a Novel Scale That Quantifies the Glycemic Progression Toward Type 1 Diabetes Over 6 Months: Figure 1

Sosenko, Jay M., Skyler, Jay S., Beam, Craig A., Boulware, David, Mahon, Jeffrey L., Krischer, Jeffrey P., Greenbaum, Carla J., Rafkin, Lisa E., Matheson, Della, Herold, Kevan C., Palmer, Jerry P.

Journal:

Year:

2015

Language:

english

File:

PDF, 1.44 MB

english, 2015

26

Two- and Four-Hour Tests Differ in Capture of C-Peptide Responses to a Mixed Meal in Type 1 Diabetes

Boyle, Karen D., Keyes-Elstein, Lynette, Ehlers, Mario R., McNamara, James, Rigby, Mark R., Gitelman, Stephen E., Weiner, Lia J., Much, Kristen L., Herold, Kevan C.

Journal:

Year:

2016

Language:

english

File:

PDF, 2.19 MB

english, 2016

27

Early and Late Câpeptide Responses during Oral Glucose Tolerance Testing are Oppositely Predictive of Type 1 Diabetes in Autoantibody Positive Individuals

Ismail, Heba M., Becker, Dorothy J., Libman, Ingrid, Herold, Kevan C., Redondo, Maria J., Atkinson, Mark A., Cleves, Mario A, Palmer, Jerry, Sosenko, Jay

Journal:

Diabetes, Obesity and Metabolism

Year:

2020

Language:

english

File:

PDF, 239 KB

english, 2020

28

Invited commentary

Kevan C. Herold, Edwin L. Kaplan

Journal:

World Journal of Surgery

Year:

1986

Language:

english

File:

PDF, 201 KB

english, 1986

29

Development of Latest-generation HU-PBMC-NOD/SCID Mice to Study Human Islet Allo-reactivity

Todd Pearson, Marie King, Leonard Shultz, Jean Leif, Dale Greiner, John Mordes, Aldo Rossini, Mark Atkinson, Clive Wasserfall, Massimo Trucco, Kevan Herold, Rita Botti

Journal:

Clinical Immunology

Year:

2007

Language:

english

File:

PDF, 41 KB

english, 2007

30

Expression and Immune Response to Islet Antigens following Treatment with Low Doses of Streptozotocin in H-2dMice

Kevan C. Herold, Elizabeth Baumann, Vaiva Vezys, Frank Buckingham

Journal:

Journal of Autoimmunity

Year:

1997

Language:

english

File:

PDF, 347 KB

english, 1997

31

Clinical and molecular heterogeneity of familial hyperinsulinism

Benjamin Glaser, Paul S. Thornton, Kevan Herold, Charles A. Stanley

Journal:

The Journal of Pediatrics

Year:

1998

Language:

english

File:

PDF, 348 KB

english, 1998

32

Comparing Beta Cell Preservation Across Clinical Trials in Recent-Onset Type 1 Diabetes

Jacobsen, Laura, Bundy, Brian, Greco, Madison, Schatz, Desmond, Atkinson, Mark, Brusko, Todd, Mathews, Clayton, Herold, Kevan C., Gitelman, Stephen, Krischer, Jeffrey, Haller, Michael

Journal:

Diabetes Technology & Therapeutics

Year:

2020

File:

PDF, 739 KB

2020

33

Type 1 diabetes as a relapsing–remitting disease?

von Herrath, Matthias, Sanda, Srinath, Herold, Kevan

Journal:

Nature Reviews Immunology

Year:

2007

Language:

english

File:

PDF, 402 KB

english, 2007

34

Lessons from New York City—how diabetes might be affecting overall rates of coronary heart disease

Herold, Kevan C

Journal:

Nature Clinical Practice Endocrinology and Metabolism

Year:

2006

Language:

english

File:

PDF, 91 KB

english, 2006

35

Sodium chloride inhibits the suppressive function of FOXP3+ regulatory T cells

Hernandez, Amanda L., Kitz, Alexandra, Wu, Chuan, Lowther, Daniel E., Rodriguez, Donald M., Vudattu, Nalini, Deng, Songyan, Herold, Kevan C., Kuchroo, Vijay K., Kleinewietfeld, Markus, Hafler, David A

Journal:

The Journal of clinical investigation

Year:

2015

Language:

english

File:

PDF, 1.09 MB

english, 2015

36

Acquisition of regulatory function by human CD8+ T cells treated with anti-CD3 antibody requires TNF

Vitaly Ablamunits, Brygida Bisikirska, Kevan C. Herold

Journal:

European Journal of Immunology

Year:

2010

Language:

english

File:

PDF, 530 KB

english, 2010

37

The ligand/RAGE axis: Lighting the fuse and igniting vascular stress

Shi Fang Yan, Yoshifumi Naka, Barry I. Hudson, Kevan Herold, Shi Du Yan, Ravichandran Ramasamy, Ann Marie Schmidt

Journal:

Current Atherosclerosis Reports

Year:

2006

Language:

english

File:

PDF, 258 KB

english, 2006

38

Treatment of patients with new onset Type 1 diabetes with a single course of anti-CD3 mAb teplizumab preserves insulin production for up to 5 years

Kevan C. Herold, Stephen Gitelman, Carla Greenbaum, Jennifer Puck, William Hagopian, Peter Gottlieb, Peter Sayre, Peter Bianchine, Emelita Wong, Vicki Seyfert-Margolis, Kasia Bourcier, Jeffrey A. Blue

Journal:

Clinical Immunology

Year:

2009

Language:

english

File:

PDF, 449 KB

english, 2009

39

Expansion and redifferentiation of adult human pancreatic islet cells

Limor Ouziel-Yahalom, Michal Zalzman, Leeat Anker-Kitai, Sarah Knoller, Yael Bar, Mariela Glandt, Kevan Herold, Shimon Efrat

Journal:

Biochemical and Biophysical Research Communications

Year:

2006

Language:

english

File:

PDF, 553 KB

english, 2006

40

A patient with type B insulin resistance syndrome, responsive to immune therapy

Page, Kathleen A, Dejardin, Stephanie, Kahn, C Ronald, Kulkarni, Rohit N, Herold, Kevan C, Inzucchi, Silvio E

Journal:

Nature Clinical Practice Endocrinology and Metabolism

Year:

2007

Language:

english

File:

PDF, 213 KB

english, 2007

41

MAIT Cells: A Link between Gut Integrity and Type 1 Diabetes

Gülden, Elke, Palm, Noah, Herold, Kevan C.

Journal:

Cell Metabolism

Year:

2017

Language:

english

File:

PDF, 622 KB

english, 2017

42

Inducing and Administering Tregs to Treat Human Disease

Perdigoto, Ana Luisa, Chatenoud, Lucienne, Bluestone, Jeffrey A., Herold, Kevan C.

Journal:

Frontiers in Immunology

Year:

2016

Language:

english

File:

PDF, 451 KB

english, 2016

43

Anti-CD3 Monoclonal Antibody in New-Onset Type 1 Diabetes Mellitus

Herold, Kevan C., Hagopian, William, Auger, Julie A., Poumian-Ruiz, Ena, Taylor, Lesley, Donaldson, David, Gitelman, Stephen E., Harlan, David M., Xu, Danlin, Zivin, Robert A.

Journal:

Boston Medical and Surgical Journal

Year:

2002

Language:

english

File:

PDF, 110 KB

english, 2002

44

Monitoring of antigen-specific CD8 T cells in patients with type 1 diabetes treated with antiCD3 monoclonal antibodies

Simona Cernea, Kevan C. Herold

Journal:

Clinical Immunology

Year:

2010

Language:

english

File:

PDF, 934 KB

english, 2010

45

Synergy of IL-1 Receptor Antagonist and Anti-CD3 Monoclonal Antibody in Reversal of Diabetes in NOD Mice

Vitaly Ablamunits, Lynn Opare-Addo, Octavian Henegariu, Thomas Mandrup-Poulsen, Kevan Herold

Journal:

Clinical Immunology

Year:

2010

Language:

english

File:

PDF, 45 KB

english, 2010

46

Comparison of human fetal liver, umbilical cord blood, and adult blood hematopoietic stem cell engraftment in NOD-scid/γc−/−, Balb/c-Rag1−/−γc−/−, and C.B-17-scid/bg immunodeficient mice

Christin M. Lepus, Thomas F. Gibson, Scott A. Gerber, Ivana Kawikova, Marian Szczepanik, Jaber Hossain, Vitaly Ablamunits, Nancy Kirkiles-Smith, Kevan C. Herold, Ruben O. Donis, Alfred L. Bothwell, Jo

Journal:

Human Immunology

Year:

2009

Language:

english

File:

PDF, 5.48 MB

english, 2009

47

Thinking bedside at the bench: the NOD mouse model of T1DM

Reed, James C., Herold, Kevan C.

Journal:

Nature Reviews Endocrinology (formerly Nature Clinical Practice Endocrinology & Metabolism)

Year:

2015

Language:

english

File:

PDF, 147 KB

english, 2015

48

β Cell death and dysfunction during type 1 diabetes development in at-risk individuals

Herold, Kevan C., Usmani-Brown, Sahar, Ghazi, Tara, Lebastchi, Jasmin, Beam, Craig A., Bellin, Melena D., Ledizet, Michel, Sosenko, Jay M., Krischer, Jeffrey P., Palmer, Jerry P.

Journal:

Journal of Clinical Investigation

Year:

2015

Language:

english

File:

PDF, 837 KB

english, 2015

49

Immunosuppression for Insulin-Dependent Diabetes

Herold, Kevan C., Rubenstein, Arthur H.

Journal:

Boston Medical and Surgical Journal

Year:

1988

File:

PDF, 579 KB

1988

50

PREVENTION OF THE HUMORAL RESPONSE INDUCED BY AN ANTI-CD3 MONOCLONAL ANTIBODY BY DEOXYSPERGUALIN IN A MURINE MODEL1

Alegre, Maria-Luisa, Sattar, Husain A., Herold, Kevan C., Smith, Judy, Tepper, Mark A., Bluestone, Jeffrey A.

Journal:

Transplantation Journal

Year:

1994

File:

PDF, 941 KB

1994

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